Direct R-Loop Visualization on Genomic DNA by Native Automated Electron Microscopy.

Stoy, Henriette; Luethi, Joel; Roessler, Fabienne K; Riemann, Johannes; Kaech, Andres; Lopes, Massimo

Stoy, Henriette; Luethi, Joel; Roessler, Fabienne K; Riemann, Johannes; Kaech, Andres; Lopes, Massimo.

Afiliação

Stoy H; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland.
Luethi J; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland.
Roessler FK; Center for Microscopy and Image Analysis, University of Zurich, Zurich, Switzerland.
Riemann J; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
Kaech A; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland.
Lopes M; Center for Microscopy and Image Analysis, University of Zurich, Zurich, Switzerland.

Methods Mol Biol ; 2528: 1-20, 2022.

Article em En | MEDLINE | ID: mdl-35704181

Assuntos

Instabilidade Genômica; Estruturas R-Loop; DNA/química; DNA/genética; Dano ao DNA; Replicação do DNA; Genômica; Humanos; Microscopia Eletrônica; RNA/genética

Palavras-chave

Automated workflow; DNA content assessment; DNA replication; DNARNA hybrid; Direct visualization; Electron microscopy; R-loops; Single-molecule analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Instabilidade Genômica / Estruturas R-Loop Limite: Humans Idioma: En Revista: Methods Mol Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça

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