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Synthesis and biological evaluation of tyrosine derivatives as peripheral 5HT2A receptor antagonists for nonalcoholic fatty liver disease.
Kim, Minhee; Choi, Wonil; Yoon, Jihyeon; Jeong, Byung-Kwan; Pagire, Suvarna H; Pagire, Haushabhau S; Park, Jungsun; Nam, Jung Eun; Oh, Chang Joo; Jeon, Jae-Han; Kim, Seong Soon; Lee, Byung Hoi; Song, Jin Sook; Bae, Myung Ae; Lee, In-Kyu; Kim, Hail; Ahn, Jin Hee.
Afiliação
  • Kim M; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju, 61005, South Korea.
  • Choi W; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea; Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea.
  • Yoon J; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju, 61005, South Korea.
  • Jeong BK; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea; Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea.
  • Pagire SH; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju, 61005, South Korea.
  • Pagire HS; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju, 61005, South Korea.
  • Park J; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea; Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea.
  • Nam JE; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea; Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea.
  • Oh CJ; Leading-edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital, Daegu, South Korea.
  • Jeon JH; Leading-edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital, Daegu, South Korea; Department of Internal Medicine, Kyungpook National University Hospital and School of Medicine, Kyungpook National University, Daegu, 700-72
  • Kim SS; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon, South Korea.
  • Lee BH; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon, South Korea.
  • Song JS; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon, South Korea.
  • Bae MA; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon, South Korea.
  • Lee IK; Leading-edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital, Daegu, South Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Kor
  • Kim H; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea; Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea. Electronic address: hail
  • Ahn JH; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju, 61005, South Korea; JD Bioscience, 208 Cheomdan-dwagiro, Buk-gu, Gwangju, 61005, South Korea. Electronic address: jhahn@gist.ac.kr.
Eur J Med Chem ; 239: 114517, 2022 Sep 05.
Article em En | MEDLINE | ID: mdl-35732081
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Hepatopatia Gordurosa não Alcoólica / Neoplasias Hepáticas Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Coréia do Sul
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Hepatopatia Gordurosa não Alcoólica / Neoplasias Hepáticas Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Coréia do Sul