Application of a Physiologically Based Pharmacokinetic Model to Predict Cefazolin and Cefuroxime Disposition in Obese Pregnant Women Undergoing Caesarean Section.

Alrammaal, Hanadi H; Abduljalil, Khaled; Hodgetts Morton, Victoria; Morris, R Katie; Marriott, John F; Chong, Hsu P; Batchelor, Hannah K

Alrammaal, Hanadi H; Abduljalil, Khaled; Hodgetts Morton, Victoria; Morris, R Katie; Marriott, John F; Chong, Hsu P; Batchelor, Hannah K.

Afiliação

Alrammaal HH; School of Pharmacy, Institute of Clinical Sciences, University of Birmingham, Birmingham B15 2TT, UK.
Abduljalil K; Clinical Pharmacy Department, Collage of Pharmacy, Umm Al-Qura University, Mecca 24382, Saudi Arabia.
Hodgetts Morton V; Simcyp Division, Certara UK Limited, Sheffield S1 2BJ, UK.
Morris RK; Department of Fetal and Maternal Medicine, Birmingham Women's and Children's NHS Foundation Trust, Birmingham B15 2TG, UK.
Marriott JF; Institute for Metabolic and Systems Research, University of Birmingham, Birmingham B15 2TT, UK.
Chong HP; Department of Fetal and Maternal Medicine, Birmingham Women's and Children's NHS Foundation Trust, Birmingham B15 2TG, UK.
Batchelor HK; Institute for Metabolic and Systems Research, University of Birmingham, Birmingham B15 2TT, UK.

Pharmaceutics ; 14(6)2022 May 30.

Article em En | MEDLINE | ID: mdl-35745736

Palavras-chave

adipose exposure; caesarean section; cefazolin; cefuroxime; obese pregnant; physiologically-based pharmacokinetic model

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Pharmaceutics Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

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