Dual-Luciferase-Based Fast and Sensitive Detection of Malaria Hypnozoites for the Discovery of Anti-relapse Compounds.

Voorberg-van der Wel, Annemarie M; Zeeman, Anne-Marie; Nieuwenhuis, Ivonne G; van der Werff, Nicole M; Kocken, Clemens H M

Voorberg-van der Wel, Annemarie M; Zeeman, Anne-Marie; Nieuwenhuis, Ivonne G; van der Werff, Nicole M; Kocken, Clemens H M.

Afiliação

Voorberg-van der Wel AM; Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Zeeman AM; Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Nieuwenhuis IG; Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
van der Werff NM; Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Kocken CHM; Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands. kocken@bprc.nl.

Methods Mol Biol ; 2524: 397-408, 2022.

Article em En | MEDLINE | ID: mdl-35821489

Assuntos

Malária; Plasmodium cynomolgi; Hepatócitos; Humanos; Luciferases/genética; Malária/diagnóstico; Malária/parasitologia; Plasmodium cynomolgi/fisiologia; Recidiva

Palavras-chave

Bioluminescence (BL); Drug screening; Dual; Firefly luciferase; Hepatocytes; Hypnozoites; Liver; Liver stages; Malaria; Monkeys; NanoLuc; Plasmodium cynomolgi; Sporozoites

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 / 3_ND Problema de saúde: 2_enfermedades_transmissibles / 3_malaria / 3_neglected_diseases / 3_zoonosis Assunto principal: Plasmodium cynomolgi / Malária Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Methods Mol Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda

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