The secondary pocket of cryptochrome 2 is important for the regulation of its stability and localization.

Parlak, Gizem Cagla; Camur, Bilge Bahar; Gul, Seref; Ozcan, Onur; Baris, Ibrahim; Kavakli, Ibrahim Halil

Parlak, Gizem Cagla; Camur, Bilge Bahar; Gul, Seref; Ozcan, Onur; Baris, Ibrahim; Kavakli, Ibrahim Halil.

Afiliação

Parlak GC; Department of Molecular Biology and Genetics, Koc University, Istanbul, Turkey.
Camur BB; Department of Molecular Biology and Genetics, Koc University, Istanbul, Turkey.
Gul S; Biotechnology Division, Department of Biology, Istanbul University, Istanbul, Turkey.
Ozcan O; Department of Molecular Biology and Genetics, Koc University, Istanbul, Turkey.
Baris I; Department of Molecular Biology and Genetics, Koc University, Istanbul, Turkey.
Kavakli IH; Department of Molecular Biology and Genetics, Koc University, Istanbul, Turkey; Department of Chemical and Biological Engineering, Koc University, Istanbul, Turkey. Electronic address: hkavakli@ku.edu.tr.

J Biol Chem ; 298(9): 102334, 2022 09.

Article em En | MEDLINE | ID: mdl-35933018

Assuntos

Fatores de Transcrição ARNTL; Proteínas CLOCK; Ritmo Circadiano; Criptocromos; Fatores de Transcrição ARNTL/metabolismo; Animais; Proteínas CLOCK/metabolismo; Ritmo Circadiano/fisiologia; Criptocromos/química; Criptocromos/genética; Criptocromos/metabolismo; Fibroblastos; Humanos; Camundongos; Domínios Proteicos; Estabilidade Proteica

Palavras-chave

SNP; circadian clock; cryptochrome; nuclear transport; protein stability

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ritmo Circadiano / Proteínas CLOCK / Fatores de Transcrição ARNTL / Criptocromos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Turquia

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