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Safety, Tolerability, and Parasite Clearance Kinetics in Controlled Human Malaria Infection after Direct Venous Inoculation of Plasmodium falciparum Sporozoites: A Model for Evaluating New Blood-Stage Antimalarial Drugs.
Chughlay, M Farouk; Chalon, Stephan; El Gaaloul, Myriam; Gobeau, Nathalie; Möhrle, Jörg J; Berghmans, Pieter-Jan; Van Leuven, Katrin; Marx, Michael W; Rosanas-Urgell, Anna; Flynn, Julia; Escoffier, Emilie; Izquierdo-Juncàs, Daniel; Jansen, Bastiaan; Mitov, Venelin; Kümmel, Anne; Van Geertruyden, Jean-Pierre; Barnes, Karen I.
Afiliação
  • Chughlay MF; Medicines for Malaria Venture, Geneva, Switzerland.
  • Chalon S; Medicines for Malaria Venture, Geneva, Switzerland.
  • El Gaaloul M; Medicines for Malaria Venture, Geneva, Switzerland.
  • Gobeau N; Medicines for Malaria Venture, Geneva, Switzerland.
  • Möhrle JJ; Medicines for Malaria Venture, Geneva, Switzerland.
  • Berghmans PJ; SGS Life Sciences, Antwerp, Belgium.
  • Van Leuven K; SGS Life Sciences, Antwerp, Belgium.
  • Marx MW; ICON Clinical Research GmbH, Langen, Germany.
  • Rosanas-Urgell A; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
  • Flynn J; Medicines for Malaria Venture, Geneva, Switzerland.
  • Escoffier E; Medicines for Malaria Venture, Geneva, Switzerland.
  • Izquierdo-Juncàs D; SGS Life Sciences, Antwerp, Belgium.
  • Jansen B; SGS Life Sciences, Antwerp, Belgium.
  • Mitov V; IntiQuan GmbH, Basel, Switzerland.
  • Kümmel A; IntiQuan GmbH, Basel, Switzerland.
  • Van Geertruyden JP; Global Health Institute, University of Antwerp, Antwerp, Belgium.
  • Barnes KI; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.
Am J Trop Med Hyg ; 107(4): 804-814, 2022 10 12.
Article em En | MEDLINE | ID: mdl-36037868
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 3_ND Problema de saúde: 1_doencas_transmissiveis / 2_enfermedades_transmissibles / 3_malaria / 3_neglected_diseases / 3_zoonosis Assunto principal: Parasitos / Malária / Antimaláricos Limite: Adult / Animals / Humans Idioma: En Revista: Am J Trop Med Hyg Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 3_ND Problema de saúde: 1_doencas_transmissiveis / 2_enfermedades_transmissibles / 3_malaria / 3_neglected_diseases / 3_zoonosis Assunto principal: Parasitos / Malária / Antimaláricos Limite: Adult / Animals / Humans Idioma: En Revista: Am J Trop Med Hyg Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça