Fisetin ameliorates oxidative glutamate testicular toxicity in rats via central and peripheral mechanisms involving SIRT1 activation.

Rizk, Fatma H; Soliman, Nema A; Abo-Elnasr, Suzan E; Mahmoud, Heba A; Abdel Ghafar, Muhammad T; Elkholy, Rasha A; ELshora, Ola A; Mariah, Reham A; Amin Mashal, Shaimaa Samir; El Saadany, Amira A

Rizk, Fatma H; Soliman, Nema A; Abo-Elnasr, Suzan E; Mahmoud, Heba A; Abdel Ghafar, Muhammad T; Elkholy, Rasha A; ELshora, Ola A; Mariah, Reham A; Amin Mashal, Shaimaa Samir; El Saadany, Amira A.

Afiliação

Rizk FH; Department of Medical Physiology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Soliman NA; Department of Medical Biochemistry, Faculty of Medicine, Tanta University, Tanta, Egypt.
Abo-Elnasr SE; Department of Histology and Cell Biology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Mahmoud HA; Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Abdel Ghafar MT; Department of Clinical Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Elkholy RA; Department of Clinical Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt.
ELshora OA; Department of Clinical Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Mariah RA; Department of Medical Biochemistry, Faculty of Medicine, Tanta University, Tanta, Egypt.
Amin Mashal SS; Department of Internal Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.
El Saadany AA; Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt.

Redox Rep ; 27(1): 177-185, 2022 Dec.

Article em En | MEDLINE | ID: mdl-36047349

Assuntos

Flavonóis; Sirtuína 1; Testículo; Animais; Flavonóis/farmacologia; Hormônio Foliculoestimulante/metabolismo; Hormônio Liberador de Gonadotropina/metabolismo; Peróxido de Hidrogênio/metabolismo; Masculino; Estresse Oxidativo; Ratos; Sêmen/metabolismo; Sirtuína 1/metabolismo; Glutamato de Sódio/toxicidade; Testículo/efeitos dos fármacos; Testosterona/metabolismo

Palavras-chave

Monosodium glutamate; NOX4; SIRT1; fisetin; hypothalamic-pituitary-gonadal axis; oxidative stress; reduced glutathione; testicular toxicity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testículo / Flavonóis / Sirtuína 1 Limite: Animals Idioma: En Revista: Redox Rep Assunto da revista: BIOQUIMICA / METABOLISMO Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Egito

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