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Pegcetacoplan versus eculizumab in patients with paroxysmal nocturnal haemoglobinuria (PEGASUS): 48-week follow-up of a randomised, open-label, phase 3, active-comparator, controlled trial.
de Latour, Régis Peffault; Szer, Jeff; Weitz, Ilene C; Röth, Alexander; Höchsmann, Britta; Panse, Jens; Usuki, Kensuke; Griffin, Morag; Kiladjian, Jean-Jacques; de Castro, Carlos M; Nishimori, Hisakazu; Ajayi, Temitayo; Al-Adhami, Mohammed; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Risitano, Antonio M; Hillmen, Peter.
Afiliação
  • de Latour RP; French Reference Center for Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria, Université Paris Cité, Saint-Louis Hospital, Paris, France; Assistance Publique-Hôpitaux de Paris, Department of Hematology and Bone Marrow Transplantation, Saint-Louis Hospital, Université Paris Cité, Paris, France
  • Szer J; Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC, Australia.
  • Weitz IC; Jane Anne Nohl Division of Hematology, Keck-University of Southern California School of Medicine, Los Angeles, CA, USA.
  • Röth A; Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Höchsmann B; Institute of Transfusion Medicine, University of Ulm, Ulm, Germany; Institute of Clinical Transfusion Medicine and Immunogenetics, German Red Cross Blood Transfusion Service, Baden-Württemberg-Hessen and University Hospital of Ulm, Ulm, Germany.
  • Panse J; Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, University Hospital RWTH Aachen, Aachen, Germany; Center for Integrated Oncology, Aachen Bonn Cologne Düsseldorf, Aachen, Germany.
  • Usuki K; Department of Hematology, NTT Medical Center Tokyo, Tokyo, Japan.
  • Griffin M; Department of Haematology, Saint James University Hospital, Leeds, UK.
  • Kiladjian JJ; Université Paris Cité, Assistance Publique-Hôpitaux de Paris, Hoôpital Saint-Louis, Centre d'Investigations Cliniques, INSERM, CIC1427, Paris, France.
  • de Castro CM; Department of Medicine, Division of Hematologic Malignancies and Cellular Therapy, Duke University, Durham, NC, USA.
  • Nishimori H; Department of Hematology and Oncology, Okayama University Hospital, Okayama, Japan.
  • Ajayi T; Apellis Pharmaceuticals, Waltham, MA, USA.
  • Al-Adhami M; Apellis Pharmaceuticals, Waltham, MA, USA.
  • Deschatelets P; Apellis Pharmaceuticals, Waltham, MA, USA.
  • Francois C; Apellis Pharmaceuticals, Waltham, MA, USA.
  • Grossi F; Apellis Pharmaceuticals, Waltham, MA, USA.
  • Risitano AM; Hematology and BMT Unit, AORN San Giuseppe Moscati, Avellino, Italy; Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy.
  • Hillmen P; Department of Haematology, Saint James University Hospital, Leeds, UK.
Lancet Haematol ; 9(9): e648-e659, 2022 Sep.
Article em En | MEDLINE | ID: mdl-36055332
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 3_ND / 4_TD Problema de saúde: 1_doencas_nao_transmissiveis / 3_diarrhea / 4_diarrhoeal_infections Assunto principal: Hemoglobinúria Paroxística Tipo de estudo: Clinical_trials / Guideline / Observational_studies / Prognostic_studies Aspecto: Patient_preference Limite: Adult / Female / Humans / Male Idioma: En Revista: Lancet Haematol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 3_ND / 4_TD Problema de saúde: 1_doencas_nao_transmissiveis / 3_diarrhea / 4_diarrhoeal_infections Assunto principal: Hemoglobinúria Paroxística Tipo de estudo: Clinical_trials / Guideline / Observational_studies / Prognostic_studies Aspecto: Patient_preference Limite: Adult / Female / Humans / Male Idioma: En Revista: Lancet Haematol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França