Characterizing Genomics Repositories Using Feature-Based Classification.
Stud Health Technol Inform
; 298: 167-168, 2022 Aug 31.
Article
em En
| MEDLINE
| ID: mdl-36073480
ABSTRACT
In the last decades, the field of metagenomics aided by NGS technologies has grown exponentially and is now a cornerstone tool in medicine. However, even with the current technologies, obtaining a conclusive identification of an organism can be challenging due to using reference-based methods. Consequently, when releasing a new repository of genomic data that contains de-novo sequences, it is problematic to characterize its content. In this paper, we propose a novel method for organism identification and the creation and characterization of genomic databases. For identification, we propose a three-step pipeline for reference-free reconstruction, reference-based classification and features-based classification. On the other hand, for content exposition and extraction, the sequences and their identification are aggregated into a web database catalogue.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Genoma
/
Genômica
Idioma:
En
Revista:
Stud Health Technol Inform
Assunto da revista:
INFORMATICA MEDICA
/
PESQUISA EM SERVICOS DE SAUDE
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Portugal