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Metabolic targeting of NRF2 potentiates the efficacy of the TRAP1 inhibitor G-TPP through reduction of ROS detoxification in colorectal cancer.
Tsai, Hong-Yuan; Bronner, Mary P; March, Jordon K; Valentine, John F; Shroyer, Noah F; Lai, Lisa A; Brentnall, Teresa A; Pan, Sheng; Chen, Ru.
Afiliação
  • Tsai HY; Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA. Electronic address: Hong-Yuan.Tsai@bcm.edu.
  • Bronner MP; Department of Pathology, University of Utah, Salt Lake City, UT, USA; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
  • March JK; Department of Pathology, University of Utah, Salt Lake City, UT, USA.
  • Valentine JF; Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.
  • Shroyer NF; Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Lai LA; Department of Medicine, University of Washington, Seattle, WA, USA.
  • Brentnall TA; Department of Medicine, University of Washington, Seattle, WA, USA.
  • Pan S; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Chen R; Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA. Electronic address: ru.chen@bcm.edu.
Cancer Lett ; 549: 215915, 2022 11 28.
Article em En | MEDLINE | ID: mdl-36113636
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 1_doencas_nao_transmissiveis / 2_muertes_prematuras_enfermedades_notrasmisibles / 6_colon_rectum_cancers Assunto principal: Neoplasias Colorretais / Neoplasias do Colo Limite: Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 1_doencas_nao_transmissiveis / 2_muertes_prematuras_enfermedades_notrasmisibles / 6_colon_rectum_cancers Assunto principal: Neoplasias Colorretais / Neoplasias do Colo Limite: Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2022 Tipo de documento: Article