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Inhibition of the Phosphatidylinositol-3 Kinase Pathway Using Bimiralisib in Loss-of-Function NOTCH1-Mutant Head and Neck Cancer.
Johnson, Faye M; Janku, Filip; Gouda, Mohamed A; Tran, Hai T; Kawedia, Jitesh D; Schmitz, Debora; Streefkerk, Hendrik; Lee, J Jack; Andersen, Clark R; Deng, Defeng; Rawal, Seema; Shah, Pooja A; El-Naggar, Adel K; Johnson, Jason M; Frederick, Mitchell J.
Afiliação
  • Johnson FM; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Janku F; The University of Texas Graduate School of Biomedical Sciences, Houston, TX, USA.
  • Gouda MA; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Tran HT; Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Kawedia JD; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Schmitz D; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Streefkerk H; Department of Pharmacy Pharmacology Research, Division of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Lee JJ; PIQUR Therapeutics AG, Basel, Switzerland.
  • Andersen CR; PIQUR Therapeutics AG, Basel, Switzerland.
  • Deng D; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Rawal S; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Shah PA; Department of Otolaryngology, Baylor College of Medicine, Houston, TX, USA.
  • El-Naggar AK; Department of Otolaryngology, Baylor College of Medicine, Houston, TX, USA.
  • Johnson JM; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Frederick MJ; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Oncologist ; 27(12): 1004-e926, 2022 12 09.
Article em En | MEDLINE | ID: mdl-36124629
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatidilinositol 3-Quinase / Neoplasias de Cabeça e Pescoço Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Oncologist Assunto da revista: NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatidilinositol 3-Quinase / Neoplasias de Cabeça e Pescoço Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Oncologist Assunto da revista: NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos