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A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo.
Chan, Jasper Fuk-Woo; Oh, Yoo Jin; Yuan, Shuofeng; Chu, Hin; Yeung, Man-Lung; Canena, Daniel; Chan, Chris Chung-Sing; Poon, Vincent Kwok-Man; Chan, Chris Chun-Yiu; Zhang, Anna Jinxia; Cai, Jian-Piao; Ye, Zi-Wei; Wen, Lei; Yuen, Terrence Tsz-Tai; Chik, Kenn Ka-Heng; Shuai, Huiping; Wang, Yixin; Hou, Yuxin; Luo, Cuiting; Chan, Wan-Mui; Qin, Zhenzhi; Sit, Ko-Yung; Au, Wing-Kuk; Legendre, Maureen; Zhu, Rong; Hain, Lisa; Seferovic, Hannah; Tampé, Robert; To, Kelvin Kai-Wang; Chan, Kwok-Hung; Thomas, Dafydd Gareth; Klausberger, Miriam; Xu, Cheng; Moon, James J; Stadlmann, Johannes; Penninger, Josef M; Oostenbrink, Chris; Hinterdorfer, Peter; Yuen, Kwok-Yung; Markovitz, David M.
Afiliação
  • Chan JF; State Key Laboratory of Emerging Infectious Diseases, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrati
  • Oh YJ; Department of Experimental Applied Biophysics, Johannes Kepler University Linz, Linz, Austria.
  • Yuan S; State Key Laboratory of Emerging Infectious Diseases, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrati
  • Chu H; State Key Laboratory of Emerging Infectious Diseases, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrati
  • Yeung ML; State Key Laboratory of Emerging Infectious Diseases, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrati
  • Canena D; Department of Experimental Applied Biophysics, Johannes Kepler University Linz, Linz, Austria.
  • Chan CC; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong Special Administrative
  • Poon VK; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong Special Administrative
  • Chan CC; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Zhang AJ; State Key Laboratory of Emerging Infectious Diseases, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrati
  • Cai JP; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Ye ZW; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Wen L; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Yuen TT; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Chik KK; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong Special Administrative
  • Shuai H; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong Special Administrative
  • Wang Y; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Hou Y; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Luo C; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Chan WM; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Qin Z; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Sit KY; Department of Surgery, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Au WK; Department of Surgery, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Legendre M; Division of Infectious Diseases, Department of Internal Medicine, and the Programs in Immunology, Cellular and Molecular Biology, and Cancer Biology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Zhu R; Department of Experimental Applied Biophysics, Johannes Kepler University Linz, Linz, Austria.
  • Hain L; Department of Experimental Applied Biophysics, Johannes Kepler University Linz, Linz, Austria.
  • Seferovic H; Department of Experimental Applied Biophysics, Johannes Kepler University Linz, Linz, Austria.
  • Tampé R; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt, Germany.
  • To KK; State Key Laboratory of Emerging Infectious Diseases, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrati
  • Chan KH; State Key Laboratory of Emerging Infectious Diseases, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrati
  • Thomas DG; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Klausberger M; Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria.
  • Xu C; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA; Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  • Moon JJ; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA; Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  • Stadlmann J; Department of Chemistry, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria.
  • Penninger JM; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna, Austria; Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Oostenbrink C; Institute for Molecular Modelling and Simulation, Department of Material Science and Process Engineering, University of Natural Resources and Life Sciences, Vienna, Austria.
  • Hinterdorfer P; Department of Experimental Applied Biophysics, Johannes Kepler University Linz, Linz, Austria. Electronic address: peter.hinterdorfer@jku.at.
  • Yuen KY; State Key Laboratory of Emerging Infectious Diseases, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrati
  • Markovitz DM; Division of Infectious Diseases, Department of Internal Medicine, and the Programs in Immunology, Cellular and Molecular Biology, and Cancer Biology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: dmarkov@umich.edu.
Cell Rep Med ; 3(10): 100774, 2022 10 18.
Article em En | MEDLINE | ID: mdl-36195094
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coronavírus da Síndrome Respiratória do Oriente Médio / COVID-19 Limite: Humans Idioma: En Revista: Cell Rep Med Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coronavírus da Síndrome Respiratória do Oriente Médio / COVID-19 Limite: Humans Idioma: En Revista: Cell Rep Med Ano de publicação: 2022 Tipo de documento: Article