Etomoxir, a carnitine palmitoyltransferase 1 inhibitor, combined with temozolomide reduces stemness and invasiveness in patient-derived glioblastoma tumorspheres.

Shim, Jin-Kyoung; Choi, Seonah; Yoon, Seon-Jin; Choi, Ran Joo; Park, Junseong; Lee, Eun Hee; Cho, Hye Joung; Lee, Suji; Teo, Wan-Yee; Moon, Ju Hyung; Kim, Hyun Sil; Kim, Eui Hyun; Cheong, Jae-Ho; Chang, Jong Hee; Yook, Jong In; Kang, Seok-Gu

Shim, Jin-Kyoung; Choi, Seonah; Yoon, Seon-Jin; Choi, Ran Joo; Park, Junseong; Lee, Eun Hee; Cho, Hye Joung; Lee, Suji; Teo, Wan-Yee; Moon, Ju Hyung; Kim, Hyun Sil; Kim, Eui Hyun; Cheong, Jae-Ho; Chang, Jong Hee; Yook, Jong In; Kang, Seok-Gu.

Afiliação

Shim JK; Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Choi S; Brain Tumor Translational Research Laboratory, Severance Biomedical Research Institute, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Yoon SJ; Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Choi RJ; Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Park J; Brain Tumor Translational Research Laboratory, Severance Biomedical Research Institute, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Lee EH; Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Cho HJ; Brain Tumor Translational Research Laboratory, Severance Biomedical Research Institute, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Lee S; Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Teo WY; Brain Tumor Translational Research Laboratory, Severance Biomedical Research Institute, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Moon JH; Precision Medicine Research Center, College of Medicine, The Catholic University of Korea, Seoul, 03722, Republic of Korea.
Kim HS; Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Kim EH; Brain Tumor Translational Research Laboratory, Severance Biomedical Research Institute, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Cheong JH; Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Chang JH; Brain Tumor Translational Research Laboratory, Severance Biomedical Research Institute, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Yook JI; Department of Medical Science, BK21 Plus Project for Medical Science, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Kang SG; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.

Cancer Cell Int ; 22(1): 309, 2022 Oct 11.

Article em En | MEDLINE | ID: mdl-36221088

Palavras-chave

Etomoxir; Fatty acid oxidation; Glioblastoma; Temozolomide; Tumorsphere

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cancer Cell Int Ano de publicação: 2022 Tipo de documento: Article