Ligand-induced shifts in conformational ensembles that describe transcriptional activation.

Khan, Sabab Hasan; Braet, Sean M; Koehler, Stephen John; Elacqua, Elizabeth; Anand, Ganesh Srinivasan; Okafor, C Denise

Khan, Sabab Hasan; Braet, Sean M; Koehler, Stephen John; Elacqua, Elizabeth; Anand, Ganesh Srinivasan; Okafor, C Denise.

Afiliação

Khan SH; Department of Biochemistry and Molecular Biology, Pennsylvania State University, State College, United States.
Braet SM; Department of Chemistry, Pennsylvania State University, State Park, United States.
Koehler SJ; Department of Chemistry, Pennsylvania State University, State Park, United States.
Elacqua E; Department of Chemistry, Pennsylvania State University, State Park, United States.
Anand GS; Department of Chemistry, Pennsylvania State University, State Park, United States.
Okafor CD; Department of Biochemistry and Molecular Biology, Pennsylvania State University, State College, United States.

Elife ; 112022 10 12.

Article em En | MEDLINE | ID: mdl-36222302

Assuntos

Simulação de Dinâmica Molecular; Receptores Citoplasmáticos e Nucleares; Ligantes; Conformação Molecular; Conformação Proteica; Fatores de Transcrição; Ativação Transcricional

Palavras-chave

biochemistry; chemical biology; conformational ensembles; molecular biophysics; molecular dynamics; none; nuclear receptors; protein dynamics; structural biology; transcriptional activation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Citoplasmáticos e Nucleares / Simulação de Dinâmica Molecular Tipo de estudo: Prognostic_studies Idioma: En Revista: Elife Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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