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Design, synthesis and biological evaluation of novel 4-aminopiperidine derivatives as SMO/ERK dual inhibitors.
Zhang, Jing-Jing; Zhang, Wanwan; Zhang, Lei; Hu, Mengxuan; Xu, Qi-Jie; Xu, Yungen.
Afiliação
  • Zhang JJ; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. Electronic address: jjzhangnj@163.com.
  • Zhang W; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Zhang L; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Hu M; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Xu QJ; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Xu Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. Electronic address: xyg@cpu.edu.cn.
Bioorg Med Chem ; 74: 117051, 2022 11 15.
Article em En | MEDLINE | ID: mdl-36270113
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Hedgehog / Neoplasias Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Hedgehog / Neoplasias Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article