Loss-of-function approach using mouse retinal explants showed pivotal roles of Nmnat2 in early and middle stages of retinal development.

Kuribayashi, Hiroshi; Katahira, Miku; Aihara, Makoto; Suzuki, Yutaka; Watanabe, Sumiko

Kuribayashi, Hiroshi; Katahira, Miku; Aihara, Makoto; Suzuki, Yutaka; Watanabe, Sumiko.

Afiliação

Kuribayashi H; Department of Retinal Development and Pathophysiology, The University of Tokyo, Tokyo, Japan.
Katahira M; Division of Molecular and Developmental Biology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Aihara M; Division of Molecular and Developmental Biology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Suzuki Y; Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Watanabe S; Department of Medical Genome Sciences, Graduate School of Frontier Science, The University of Tokyo, Chiba, Japan.

Mol Biol Cell ; 34(1): ar4, 2023 01 01.

Article em En | MEDLINE | ID: mdl-36322391

Assuntos

Amaurose Congênita de Leber; Nicotinamida-Nucleotídeo Adenililtransferase; Camundongos; Animais; Nicotinamida-Nucleotídeo Adenililtransferase/genética; Nicotinamida-Nucleotídeo Adenililtransferase/metabolismo; Amaurose Congênita de Leber/genética; Retina/metabolismo; Fenótipo; Neurônios/metabolismo; RNA Interferente Pequeno

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Amaurose Congênita de Leber / Nicotinamida-Nucleotídeo Adenililtransferase Limite: Animals Idioma: En Revista: Mol Biol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

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