Proteomic characterization of post-translational modifications in drug discovery.

Zhai, Lin-Hui; Chen, Kai-Feng; Hao, Bing-Bing; Tan, Min-Jia

Zhai, Lin-Hui; Chen, Kai-Feng; Hao, Bing-Bing; Tan, Min-Jia.

Afiliação

Zhai LH; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Chen KF; University of Chinese Academy of Sciences, Beijing, 100049, China.
Hao BB; Zhongshan Institute of Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Science, Zhongshan, 528400, China.
Tan MJ; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.

Acta Pharmacol Sin ; 43(12): 3112-3129, 2022 Dec.

Article em En | MEDLINE | ID: mdl-36372853

Assuntos

Processamento de Proteína Pós-Traducional; Proteômica; Espectrometria de Massas; Proteínas; Descoberta de Drogas

Palavras-chave

drug mechanism; drug target; off-target; precision medicine; protein post-translational modification; proteomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Proteômica Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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