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Biallelic TET2 mutations confer sensitivity to 5'-azacitidine in acute myeloid leukemia.
Stölzel, Friedrich; Fordham, Sarah E; Nandana, Devi; Lin, Wei-Yu; Blair, Helen; Elstob, Claire; Bell, Hayden L; Mohr, Brigitte; Ruhnke, Leo; Kunadt, Desiree; Dill, Claudia; Allsop, Daniel; Piddock, Rachel; Soura, Emmanouela-Niki; Park, Catherine; Fadly, Mohd; Rahman, Thahira; Alharbi, Abrar; Wobus, Manja; Altmann, Heidi; Röllig, Christoph; Wagenführ, Lisa; Jones, Gail L; Menne, Tobias; Jackson, Graham H; Marr, Helen J; Fitzgibbon, Jude; Onel, Kenan; Meggendorfer, Manja; Robinson, Amber; Bziuk, Zuzanna; Bowes, Emily; Heidenreich, Olaf; Haferlach, Torsten; Villar, Sara; Ariceta, Beñat; Diaz, Rosa Ayala; Altschuler, Steven J; Wu, Lani F; Prosper, Felipe; Montesinos, Pau; Martinez-Lopez, Joaquin; Bornhäuser, Martin; Allan, James M.
Afiliação
  • Stölzel F; Medical Clinic and Polyclinic I, University Hospital Dresden, Technical University of Dresden, Dresden, Germany.
  • Fordham SE; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Nandana D; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Lin WY; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Blair H; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Elstob C; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Bell HL; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Mohr B; Medical Clinic and Polyclinic I, University Hospital Dresden, Technical University of Dresden, Dresden, Germany.
  • Ruhnke L; Medical Clinic and Polyclinic I, University Hospital Dresden, Technical University of Dresden, Dresden, Germany.
  • Kunadt D; Medical Clinic and Polyclinic I, University Hospital Dresden, Technical University of Dresden, Dresden, Germany.
  • Dill C; Medical Clinic and Polyclinic I, University Hospital Dresden, Technical University of Dresden, Dresden, Germany.
  • Allsop D; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Piddock R; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Soura EN; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Park C; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Fadly M; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Rahman T; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Alharbi A; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Wobus M; Medical Clinic and Polyclinic I, University Hospital Dresden, Technical University of Dresden, Dresden, Germany.
  • Altmann H; Medical Clinic and Polyclinic I, University Hospital Dresden, Technical University of Dresden, Dresden, Germany.
  • Röllig C; Medical Clinic and Polyclinic I, University Hospital Dresden, Technical University of Dresden, Dresden, Germany.
  • Wagenführ L; Medical Clinic and Polyclinic I, University Hospital Dresden, Technical University of Dresden, Dresden, Germany.
  • Jones GL; Department of Hematology, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
  • Menne T; Department of Hematology, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
  • Jackson GH; Department of Hematology, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
  • Marr HJ; Department of Hematology, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
  • Fitzgibbon J; Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
  • Onel K; Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Meggendorfer M; MLL Munich Leukemia Laboratory, Munich, Germany.
  • Robinson A; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Bziuk Z; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Bowes E; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Heidenreich O; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Haferlach T; MLL Munich Leukemia Laboratory, Munich, Germany.
  • Villar S; Department of Hematology, Clínica Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain.
  • Ariceta B; Hematological Diseases Laboratory, CIMA LAB Diagnostics, University of Navarra, Navarra, Spain.
  • Diaz RA; IdiSNA, Navarra, Spain.
  • Altschuler SJ; Hematology Department, Hospital 12 de Octubre (i+12), Centro Nacional de Investigaciones Oncológicas (CNIO), Complutense University, Madrid, Spain.
  • Wu LF; Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, San Francisco, California, USA.
  • Prosper F; Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, San Francisco, California, USA.
  • Montesinos P; Department of Hematology, Clínica Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain.
  • Martinez-Lopez J; Hospital Universitario y Politécnico La Fe, Valencia, Spain.
  • Bornhäuser M; Hematology Department, Hospital 12 de Octubre (i+12), Centro Nacional de Investigaciones Oncológicas (CNIO), Complutense University, Madrid, Spain.
  • Allan JM; Medical Clinic and Polyclinic I, University Hospital Dresden, Technical University of Dresden, Dresden, Germany.
JCI Insight ; 8(2)2023 Jan 24.
Article em En | MEDLINE | ID: mdl-36480300

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Dioxigenases Limite: Animals / Humans Idioma: En Revista: JCI Insight Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Dioxigenases Limite: Animals / Humans Idioma: En Revista: JCI Insight Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha
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