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In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma.
Kaushik, Akash K; Tarangelo, Amy; Boroughs, Lindsey K; Ragavan, Mukundan; Zhang, Yuanyuan; Wu, Cheng-Yang; Li, Xiangyi; Ahumada, Kristen; Chiang, Jui-Chung; Tcheuyap, Vanina T; Saatchi, Faeze; Do, Quyen N; Yong, Cissy; Rosales, Tracy; Stevens, Christina; Rao, Aparna D; Faubert, Brandon; Pachnis, Panayotis; Zacharias, Lauren G; Vu, Hieu; Cai, Feng; Mathews, Thomas P; Genovese, Giannicola; Slusher, Barbara S; Kapur, Payal; Sun, Xiankai; Merritt, Matthew; Brugarolas, James; DeBerardinis, Ralph J.
Afiliação
  • Kaushik AK; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Tarangelo A; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Boroughs LK; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Ragavan M; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Zhang Y; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Wu CY; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Li X; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Ahumada K; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Chiang JC; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Tcheuyap VT; Kidney Cancer Program, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Saatchi F; Kidney Cancer Program, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Do QN; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Yong C; Department of Surgery, University of Cambridge, Cambridge, UK.
  • Rosales T; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Stevens C; Kidney Cancer Program, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Rao AD; Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
  • Faubert B; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria 3010, Australia.
  • Pachnis P; Department of Medicine, The University of Chicago, Chicago, IL, USA.
  • Zacharias LG; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Vu H; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Cai F; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Mathews TP; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Genovese G; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Slusher BS; Department of Genitourinary Medical Oncology, MD Anderson Cancer Center, Houston, TX, USA.
  • Kapur P; Department of Neurology and Johns Hopkins Drug Discovery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Sun X; Kidney Cancer Program, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Merritt M; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Brugarolas J; Kidney Cancer Program, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • DeBerardinis RJ; Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX USA.
Sci Adv ; 8(50): eabp8293, 2022 12 16.
Article em En | MEDLINE | ID: mdl-36525494

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Neoplasias Renais Limite: Animals / Humans Idioma: En Revista: Sci Adv Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Neoplasias Renais Limite: Animals / Humans Idioma: En Revista: Sci Adv Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
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