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Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2.
Miluzio, Annarita; Cuomo, Alessandro; Cordiglieri, Chiara; Donnici, Lorena; Pesce, Elisa; Bombaci, Mauro; Conti, Matteo; Fasciani, Alessandra; Terracciano, Luigi; Manganaro, Lara; Toccafondi, Mirco; Scagliola, Alessandra; Oliveto, Stefania; Ricciardi, Sara; Grifantini, Renata; De Francesco, Raffaele; Abrignani, Sergio; Manfrini, Nicola; Biffo, Stefano.
Afiliação
  • Miluzio A; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • Cuomo A; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20141, Milan, Italy.
  • Cordiglieri C; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • Donnici L; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • Pesce E; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • Bombaci M; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • Conti M; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • Fasciani A; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • Terracciano L; Institute of Pathology, University Hospital Basel, 4031, Basel, Switzerland.
  • Manganaro L; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • Toccafondi M; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • Scagliola A; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • Oliveto S; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • Ricciardi S; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy; Department of Biosciences, University of Milan, 20133, Milan, Italy.
  • Grifantini R; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy.
  • De Francesco R; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy; Department of Pharmacological and Biomolecular Sciences, University of Milan, 20133, Milan, Italy.
  • Abrignani S; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy; Department of Clinical Sciences and Community Health, University of Milan, 20122, Milan, Italy.
  • Manfrini N; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy; Department of Biosciences, University of Milan, 20133, Milan, Italy. Electronic address: manfrini@ingm.org.
  • Biffo S; National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi", INGM, 20122, Milan, Italy; Department of Biosciences, University of Milan, 20133, Milan, Italy. Electronic address: biffo@ingm.org.
EBioMedicine ; 87: 104390, 2023 Jan.
Article em En | MEDLINE | ID: mdl-36584595
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 4_TD Problema de saúde: 4_pneumonia Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: EBioMedicine Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 4_TD Problema de saúde: 4_pneumonia Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: EBioMedicine Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália