Spirometra mansoni sparganosis identified by metagenomic next-generation sequencing: a case report.
Int J Infect Dis
; 128: 128-131, 2023 Mar.
Article
em En
| MEDLINE
| ID: mdl-36592686
ABSTRACT
A 30-year-old male patient had a cyst on the left hip and progressive enlargement for more than 2 months. Combined blood tests, magnetic resonance imaging, and pathology findings, cysticercosis infection was suspected. However, the treatment for cysticercosis was ineffective. We conducted a metagenomic next-generation sequencing (mNGS) analysis on the formalin-fixed, paraffin-embedded specimen of the patient's surgically excised tissue, and the results suggested Spirometra mansoni, mNGS was further confirmed by polymerase chain reaction and phylogenetic analysis of cytochrome c oxidase subunit 1 (cox1) gene. Based on these results, we found that mNGS provided a better method of diagnosing parasitic infections.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
3_ND
Problema de saúde:
3_helminthiasis
/
3_neglected_diseases
/
3_zoonosis
Assunto principal:
Spirometra
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Cisticercose
/
Esparganose
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adult
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Animals
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Humans
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Male
Idioma:
En
Revista:
Int J Infect Dis
Assunto da revista:
DOENCAS TRANSMISSIVEIS
Ano de publicação:
2023
Tipo de documento:
Article