Nucleic acid uptake occurs independent of lysosomal acidification but dependent on ATP consumption during RNautophagy/DNautophagy.

Contu, Viorica Raluca; Sakai, Ryohei; Fujiwara, Yuuki; Kabuta, Chihana; Wada, Keiji; Kabuta, Tomohiro

Contu, Viorica Raluca; Sakai, Ryohei; Fujiwara, Yuuki; Kabuta, Chihana; Wada, Keiji; Kabuta, Tomohiro.

Afiliação

Contu VR; Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, 187-8502, Japan; Department of Neurology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo, Yamanashi, 409-38
Sakai R; Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, 187-8502, Japan.
Fujiwara Y; Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, 187-8502, Japan; Department of Child Development and Molecular Brain Science, United Graduate School of Child Development, Osaka University, Suita, Osaka
Kabuta C; Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, 187-8502, Japan.
Wada K; Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, 187-8502, Japan.
Kabuta T; Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, 187-8502, Japan. Electronic address: kabuta@ncnp.go.jp.

Biochem Biophys Res Commun ; 644: 105-111, 2023 02 12.

Article em En | MEDLINE | ID: mdl-36640664

Assuntos

Ácidos Nucleicos; ATPases Vacuolares Próton-Translocadoras; Ácidos Nucleicos/metabolismo; RNA/genética; RNA/metabolismo; Lisossomos/metabolismo; ATPases Vacuolares Próton-Translocadoras/genética; ATPases Vacuolares Próton-Translocadoras/metabolismo; Concentração de Íons de Hidrogênio; Trifosfato de Adenosina/metabolismo

Palavras-chave

Bafilomycin A1; DNautophagy; Lysosomal acidification; Nucleic acid uptake; RNautophagy; V-ATPase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Nucleicos / ATPases Vacuolares Próton-Translocadoras Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2023 Tipo de documento: Article

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