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A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene.
Gao, Yuandi; Guitton-Sert, Laure; Dessapt, Julien; Coulombe, Yan; Rodrigue, Amélie; Milano, Larissa; Blondeau, Andréanne; Larsen, Nicolai Balle; Duxin, Julien P; Hussein, Samer; Fradet-Turcotte, Amélie; Masson, Jean-Yves.
Afiliação
  • Gao Y; CHU de Québec Research Center, Oncology Division, Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, 9 McMahon, Québec City, QC, G1R 3S3, Canada.
  • Guitton-Sert L; CHU de Québec Research Center, Oncology Division, Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, 9 McMahon, Québec City, QC, G1R 3S3, Canada.
  • Dessapt J; CHU de Québec Research Center, Oncology Division, Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, 9 McMahon, Québec City, QC, G1R 3S3, Canada.
  • Coulombe Y; CHU de Québec Research Center, Oncology Division, Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, 9 McMahon, Québec City, QC, G1R 3S3, Canada.
  • Rodrigue A; CHU de Québec Research Center, Oncology Division, Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, 9 McMahon, Québec City, QC, G1R 3S3, Canada.
  • Milano L; CHU de Québec Research Center, Oncology Division, Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, 9 McMahon, Québec City, QC, G1R 3S3, Canada.
  • Blondeau A; CHU de Québec Research Center, Oncology Division, Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, 9 McMahon, Québec City, QC, G1R 3S3, Canada.
  • Larsen NB; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
  • Duxin JP; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
  • Hussein S; CHU de Québec Research Center, Oncology Division, Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, 9 McMahon, Québec City, QC, G1R 3S3, Canada.
  • Fradet-Turcotte A; CHU de Québec Research Center, Oncology Division, Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, 9 McMahon, Québec City, QC, G1R 3S3, Canada.
  • Masson JY; CHU de Québec Research Center, Oncology Division, Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, 9 McMahon, Québec City, QC, G1R 3S3, Canada. Jean-Yves.Masson@crchudequebec.ulaval.ca.
Nat Commun ; 14(1): 381, 2023 01 24.
Article em En | MEDLINE | ID: mdl-36693839
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tolerância a Medicamentos / Exodesoxirribonucleases / Anemia de Fanconi / Sistemas CRISPR-Cas / Formaldeído Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tolerância a Medicamentos / Exodesoxirribonucleases / Anemia de Fanconi / Sistemas CRISPR-Cas / Formaldeído Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá