PKI: A bioinformatics method of quantifying the importance of nodes in gene regulatory network via a pseudo knockout index.

Wang, Yijuan; Liu, Chao; Qiao, Xu; Han, Xianhua; Liu, Zhi-Ping

Wang, Yijuan; Liu, Chao; Qiao, Xu; Han, Xianhua; Liu, Zhi-Ping.

Afiliação

Wang Y; Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Jinan, Shandong 250061, China.
Liu C; Department of Orthodontics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
Qiao X; Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Jinan, Shandong 250061, China.
Han X; Faculty of Science, Yamaguchi University, Yamaguchi 753-8511, Japan.
Liu ZP; Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Jinan, Shandong 250061, China. Electronic address: zpliu@sdu.edu.cn.

Biochim Biophys Acta Gene Regul Mech ; 1866(2): 194911, 2023 06.

Article em En | MEDLINE | ID: mdl-36804477

Assuntos

Regulação da Expressão Gênica; Redes Reguladoras de Genes; Reprodutibilidade dos Testes; Biologia Computacional/métodos; Fatores de Transcrição/metabolismo

Palavras-chave

Embryonic stem cell; Gene importance evaluation; Gene regulatory network; Ordinary differential equation; Pseudo knockout index; Time series scRNA-seq data

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Redes Reguladoras de Genes Tipo de estudo: Prognostic_studies Idioma: En Revista: Biochim Biophys Acta Gene Regul Mech Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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