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Development and validation of an LC-MS/MS method for simultaneous determination of SH-1028, an irreversible third-generation EGFR TKI, and two of its metabolites in human plasma: application in clinical pharmacokinetics.
Zhou, Sufeng; Sha, Bijun; Wang, Lu; Zhao, Yuqing; Wang, Zhiqiang; Zhang, Xian; Han, Luwei; Shao, Feng; Chen, Xijing.
Afiliação
  • Zhou S; Phase I Clinical Trial Unit, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Sha B; Phase I Clinical Trial Unit, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Wang L; Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China.
  • Zhao Y; Phase I Clinical Trial Unit, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Wang Z; Phase I Clinical Trial Unit, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Zhang X; Nanjing Sanhome Pharmaceutical Co., Ltd., Nanjing, China.
  • Han L; Nanjing Sanhome Pharmaceutical Co., Ltd., Nanjing, China.
  • Shao F; Nanjing Sanhome Pharmaceutical Co., Ltd., Nanjing, China.
  • Chen X; Phase I Clinical Trial Unit, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xenobiotica ; 53(2): 84-92, 2023 Feb.
Article em En | MEDLINE | ID: mdl-36821249
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Xenobiotica Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Xenobiotica Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China