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The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection.
Goldswain, Hannah; Dong, Xiaofeng; Penrice-Randal, Rebekah; Alruwaili, Muhannad; Shawli, Ghada T; Prince, Tessa; Williamson, Maia Kavanagh; Raghwani, Jayna; Randle, Nadine; Jones, Benjamin; Donovan-Banfield, I'ah; Salguero, Francisco J; Tree, Julia A; Hall, Yper; Hartley, Catherine; Erdmann, Maximilian; Bazire, James; Jearanaiwitayakul, Tuksin; Semple, Malcolm G; Openshaw, Peter J M; Baillie, J Kenneth; Emmett, Stevan R; Digard, Paul; Matthews, David A; Turtle, Lance; Darby, Alistair C; Davidson, Andrew D; Carroll, Miles W; Hiscox, Julian A.
Afiliação
  • Goldswain H; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Dong X; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Penrice-Randal R; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Alruwaili M; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Shawli GT; Medical Laboratory Technology Department, Northern Border University, Arar City, Saudi Arabia.
  • Prince T; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Williamson MK; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Raghwani J; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.
  • Randle N; Department of Zoology, University of Oxford, Oxford, UK.
  • Jones B; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Donovan-Banfield I; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Salguero FJ; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Tree JA; NIHR Health Protection Unit in Emerging and Zoonotic Infections, Liverpool, UK.
  • Hall Y; UK Health Security Agency, Salisbury, UK.
  • Hartley C; UK Health Security Agency, Salisbury, UK.
  • Erdmann M; UK Health Security Agency, Salisbury, UK.
  • Bazire J; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Jearanaiwitayakul T; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.
  • Semple MG; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.
  • Openshaw PJM; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.
  • Baillie JK; Department of Microbiology, Mahidol University, Salaya, Thailand.
  • Emmett SR; NIHR Health Protection Unit in Emerging and Zoonotic Infections, Liverpool, UK.
  • Digard P; Department of Respiratory Medicine, Alder Hey Children's Hospital, Liverpool, UK.
  • Matthews DA; National Heart and Lung Institute, Imperial College London, London, UK.
  • Turtle L; The Roslin Institute, University of Edinburgh, Edinburgh, UK.
  • Davidson AD; Royal United Hospitals Bath NHS Foundation Trust, Bath, UK.
  • Carroll MW; Bristol Medical School, University of Bristol, Bristol, UK.
  • Hiscox JA; The Roslin Institute, University of Edinburgh, Edinburgh, UK.
Genome Biol ; 24(1): 47, 2023 03 13.
Article em En | MEDLINE | ID: mdl-36915185

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Revista: Genome Biol Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Revista: Genome Biol Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido
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