<i>CircRNA_0075723</i> protects against pneumonia-induced sepsis through inhibiting macrophage pyroptosis by sponging miR-155-5p and regulating SHIP1 expression.

Yang, Dianyin; Zhao, Dongyang; Ji, Jinlu; Wang, Chunxue; Liu, Na; Bao, Xiaowei; Liu, Xiandong; Jiang, Sen; Zhang, Qianqian; Tang, Lunxian

CircRNA_0075723 protects against pneumonia-induced sepsis through inhibiting macrophage pyroptosis by sponging miR-155-5p and regulating SHIP1 expression.

Yang, Dianyin; Zhao, Dongyang; Ji, Jinlu; Wang, Chunxue; Liu, Na; Bao, Xiaowei; Liu, Xiandong; Jiang, Sen; Zhang, Qianqian; Tang, Lunxian.

Afiliação

Yang D; Department of Internal Emergency Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Zhao D; Medical School, Tongji University, Shanghai, China.
Ji J; Department of Internal Emergency Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Wang C; Medical School, Tongji University, Shanghai, China.
Liu N; Medical School, Tongji University, Shanghai, China.
Bao X; Department of Internal Emergency Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Liu X; Medical School, Tongji University, Shanghai, China.
Jiang S; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Zhang Q; Department of Internal Emergency Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Tang L; Medical School, Tongji University, Shanghai, China.

Front Immunol ; 14: 1095457, 2023.

Article em En | MEDLINE | ID: mdl-36923408

Assuntos

MicroRNAs; Pneumonia; Sepse; Humanos; Citocinas; Células Endoteliais; Inflamassomos/genética; Inflamação; Interleucina-18; Lipopolissacarídeos; MicroRNAs/genética; Nigericina; Proteína 3 que Contém Domínio de Pirina da Família NLR/genética; Piroptose/genética; RNA Circular/genética; Sepse/genética

Palavras-chave

CircRNA_0075723; SHIP1; THP-1; miR-155-5p; pneumonia-induced sepsis; pyroptosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia / Sepse / MicroRNAs Limite: Humans Idioma: En Revista: Front Immunol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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