B cell-activating factor (BAFF) from dendritic cells, monocytes and neutrophils is required for B cell maturation and autoantibody production in SLE-like autoimmune disease.

Giordano, Daniela; Kuley, Runa; Draves, Kevin E; Elkon, Keith B; Giltiay, Natalia V; Clark, Edward A

Giordano, Daniela; Kuley, Runa; Draves, Kevin E; Elkon, Keith B; Giltiay, Natalia V; Clark, Edward A.

Afiliação

Giordano D; Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA, United States.
Kuley R; Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA, United States.
Draves KE; Department of Microbiology, University of Washington, Seattle, WA, United States.
Elkon KB; Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA, United States.
Giltiay NV; Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA, United States.
Clark EA; Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA, United States.

Front Immunol ; 14: 1050528, 2023.

Article em En | MEDLINE | ID: mdl-36923413

Assuntos

Doenças Autoimunes; Lúpus Eritematoso Sistêmico; Animais; Camundongos; Autoanticorpos; Doenças Autoimunes/metabolismo; Células Dendríticas/metabolismo; Modelos Animais de Doenças; Interleucina-4/metabolismo; Monócitos/metabolismo; Neutrófilos; Receptor 7 Toll-Like/metabolismo

Palavras-chave

B cells; BAFF; SLE; autoantibodies; autoimmunity; dendritic cells; monocytes; neutrophils

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Lúpus Eritematoso Sistêmico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Front Immunol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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