Aspartate ß-hydroxylase (ASPH) Accelerates Intrahepatic Cholangiocarcinoma Metastasis <i>via</i> Upregulating SHH Signaling Pathway.

Zou, Yiran; Lin, Jianbo; Liu, Jian; Zhang, Fabiao; Yang, Tingsong; Gong, Jian; Jiang, Tao; Zuo, Jieliang; Song, Ruimei; Shen, Hao; Shen, Feng; Li, Jun

Aspartate ß-hydroxylase (ASPH) Accelerates Intrahepatic Cholangiocarcinoma Metastasis via Upregulating SHH Signaling Pathway.

Zou, Yiran; Lin, Jianbo; Liu, Jian; Zhang, Fabiao; Yang, Tingsong; Gong, Jian; Jiang, Tao; Zuo, Jieliang; Song, Ruimei; Shen, Hao; Shen, Feng; Li, Jun.

Afiliação

Zou Y; Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, 200438, China.
Lin J; Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, 200438, China.
Liu J; Department of Hepatobiliary and Pancreatic Surgery, Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Zhang F; Department of Biliary Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, 200438, China.
Yang T; Department of Hepatobiliary Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, 317000, China.
Gong J; Department of Hepatobiliary and Pancreatic Surgery, Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Jiang T; Department of Hepatobiliary and Pancreatic Surgery, Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Zuo J; Department of Hepatobiliary and Pancreatic Surgery, Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Song R; Department of Hepatobiliary and Pancreatic Surgery, Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Shen H; Department of Hepatobiliary and Pancreatic Surgery, Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Shen F; Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, 200438, China.
Li J; International Co-operation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, Naval Medical University, Shanghai, 200438, China.

Curr Protein Pept Sci ; 24(5): 436-446, 2023.

Article em En | MEDLINE | ID: mdl-37132101

Assuntos

Ácido Aspártico; Colangiocarcinoma; Animais; Camundongos; Humanos; Glicogênio Sintase Quinase 3 beta/genética; Glicogênio Sintase Quinase 3 beta/metabolismo; Glicogênio Sintase Quinase 3 beta/farmacologia; Ácido Aspártico/farmacologia; Linhagem Celular Tumoral; Camundongos Nus; Proteínas Hedgehog/genética; Proteínas Hedgehog/metabolismo; Transdução de Sinais; Fatores de Transcrição/metabolismo; Oxigenases de Função Mista/genética; Oxigenases de Função Mista/metabolismo; Oxigenases de Função Mista/farmacologia; Colangiocarcinoma/genética; Transição Epitelial-Mesenquimal; Movimento Celular; Proteínas de Ligação ao Cálcio/metabolismo; Proteínas de Membrana/metabolismo

Palavras-chave

EMT; GLI2; GSK-3ß; Intrahepatic cholangiocarcinoma; aspartate ß-hydroxylase; sonic hedgehog

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Aspártico / Colangiocarcinoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Curr Protein Pept Sci Assunto da revista: BIOQUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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