TRPV4 expression in the renal tubule is necessary for maintaining whole body K<sup>+</sup> homeostasis.

Stavniichuk, Anna; Pyrshev, Kyrylo; Zaika, Oleg; Tomilin, Viktor N; Kordysh, Mariya; Lakk, Monika; Krizaj, David; Pochynyuk, Oleh

TRPV4 expression in the renal tubule is necessary for maintaining whole body K⁺ homeostasis.

Stavniichuk, Anna; Pyrshev, Kyrylo; Zaika, Oleg; Tomilin, Viktor N; Kordysh, Mariya; Lakk, Monika; Krizaj, David; Pochynyuk, Oleh.

Afiliação

Stavniichuk A; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.
Pyrshev K; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.
Zaika O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.
Tomilin VN; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.
Kordysh M; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.
Lakk M; Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, Utah, United States.
Krizaj D; Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, Utah, United States.
Pochynyuk O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.

Am J Physiol Renal Physiol ; 324(6): F603-F616, 2023 06 01.

Article em En | MEDLINE | ID: mdl-37141145

Assuntos

Hipopotassemia; Deficiência de Potássio; Animais; Camundongos; Adenosina Trifosfatases; Homeostase; Hipopotassemia/metabolismo; Túbulos Renais/metabolismo; Túbulos Renais Distais/metabolismo; Camundongos Knockout; Camundongos Transgênicos; Deficiência de Potássio/metabolismo; Canais de Cátion TRPV/genética; Canais de Cátion TRPV/metabolismo

Palavras-chave

distal tubule K+ transport; flow sensitivity; hyperkalemia; hypokalemia; kaliuresis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Deficiência de Potássio / Hipopotassemia Limite: Animals Idioma: En Revista: Am J Physiol Renal Physiol Assunto da revista: FISIOLOGIA / NEFROLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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