Identification of monoclonal antibody drug substances using non-destructive Raman spectroscopy.

Shukla, Mahendra K; Wilkes, Philippa; Bargary, Norma; Meagher, Katherine; Khamar, Dikshitkumar; Bailey, Donal; Hudson, Sarah P

Shukla, Mahendra K; Wilkes, Philippa; Bargary, Norma; Meagher, Katherine; Khamar, Dikshitkumar; Bailey, Donal; Hudson, Sarah P.

Afiliação

Shukla MK; SSPC, The Science Foundation Ireland Research Centre for Pharmaceuticals & Bernal Institute, University of Limerick, Limerick V94 T9PX, Ireland; Department of Chemical Sciences, University of Limerick, Limerick V94 T9PX, Ireland.
Wilkes P; SSPC, The Science Foundation Ireland Research Centre for Pharmaceuticals & Bernal Institute, University of Limerick, Limerick V94 T9PX, Ireland; Department of Mathematics and Statistics, University of Limerick, Limerick V94 T9PX, Ireland.
Bargary N; SSPC, The Science Foundation Ireland Research Centre for Pharmaceuticals & Bernal Institute, University of Limerick, Limerick V94 T9PX, Ireland; Department of Mathematics and Statistics, University of Limerick, Limerick V94 T9PX, Ireland.
Meagher K; Manufacturing Science and Technology, Sanofi Ireland, Old Kilmeaden Road, Waterford, Ireland.
Khamar D; Manufacturing Science and Technology, Sanofi Ireland, Old Kilmeaden Road, Waterford, Ireland.
Bailey D; Manufacturing Science and Technology, Sanofi Ireland, Old Kilmeaden Road, Waterford, Ireland.
Hudson SP; SSPC, The Science Foundation Ireland Research Centre for Pharmaceuticals & Bernal Institute, University of Limerick, Limerick V94 T9PX, Ireland; Department of Mathematics and Statistics, University of Limerick, Limerick V94 T9PX, Ireland. Electronic address: sarah.hudson@ul.ie.

Spectrochim Acta A Mol Biomol Spectrosc ; 299: 122872, 2023 Oct 15.

Article em En | MEDLINE | ID: mdl-37209478

Assuntos

Anticorpos Monoclonais; Análise Espectral Raman; Análise Espectral Raman/métodos; Anticorpos Monoclonais/análise; Espectrometria de Massas; Cromatografia Líquida de Alta Pressão

Palavras-chave

Chemometrics; Monoclonal antibodies; Raman spectroscopy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Análise Espectral Raman / Anticorpos Monoclonais Tipo de estudo: Diagnostic_studies / Guideline Idioma: En Revista: Spectrochim Acta A Mol Biomol Spectrosc Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Irlanda

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