A model for identification of potential phase-separated proteins based on protein sequence, structure and cellular distribution.

Wang, Jiyan; Chang, Hongkai; Quan, Xiaojing; Dai, Xintong; Wang, Yan; Wang, Chenxi; Zhang, Shuai; Shan, Changliang

Wang, Jiyan; Chang, Hongkai; Quan, Xiaojing; Dai, Xintong; Wang, Yan; Wang, Chenxi; Zhang, Shuai; Shan, Changliang.

Afiliação

Wang J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China. Electronic address: wangjiyan@nankai.edu.cn.
Chang H; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.
Quan X; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.
Dai X; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.
Wang Y; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.
Wang C; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.
Zhang S; School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China. Electronic address: shuaizhang@tjutcm.edu.cn.
Shan C; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China. Electronic address: changliangshan@nankai.edu.cn.

Int J Biol Macromol ; 243: 125196, 2023 Jul 15.

Article em En | MEDLINE | ID: mdl-37285890

Assuntos

Proteínas Intrinsicamente Desordenadas; Sequência de Aminoácidos; Proteínas Intrinsicamente Desordenadas/química; Organelas/metabolismo

Palavras-chave

AlphaFold; Cell cycle; Intrinsically disordered protein; Intrinsically disordered regions; SRSF2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Intrinsicamente Desordenadas Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2023 Tipo de documento: Article

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