Cutaneous tuberculosis as a manifestation of Pott's Disease: A diagnostic challenge in patients with Non-HIV immunosuppression.
Int J Mycobacteriol
; 12(2): 192-195, 2023.
Article
em En
| MEDLINE
| ID: mdl-37338483
ABSTRACT
Tuberculosis (TB) is one of the most important public health issues in developing countries. The World Health Organization estimates that approximately 20%-40% of the world's population is infected. Pulmonary forms account for the majority of cases; however, it can manifest as extrapulmonary disease in 8.4%-13.7% of cases. Of these extrapulmonary forms of TB, only 1%-2% may have skin manifestations. Cutaneous tuberculosis (CTB) is relatively uncommon and is not a well-defined disease, which complicates diagnosis. We present two patients with Pott's disease that manifested as CTB, one with tuberculous gumma and the other with scrofuloderma. Both patients with non-HIV immunosuppression. The diagnosis of CTB was made by detecting Mycobacterium tuberculosis in skin samples by real-time polymerase chain reaction (Xpert MTB/RIF test) and Ziehl-Neelsen staining. The histologic findings described in these two forms of TB may vary or be absent in immunosuppressed patients, making diagnosis difficult.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
10_ODS3_salud_sexual_reprodutiva
/
2_ODS3
/
3_ND
Problema de saúde:
10_sexually_transmitted_infections
/
2_cobertura_universal
/
3_neglected_diseases
/
3_tuberculosis
Assunto principal:
Tuberculose Cutânea
/
Tuberculose Pulmonar
/
Tuberculose da Coluna Vertebral
/
Mycobacterium tuberculosis
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Int J Mycobacteriol
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Colômbia