Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains.

Abendstein, Leoni; Dijkstra, Douwe J; Tjokrodirijo, Rayman T N; van Veelen, Peter A; Trouw, Leendert A; Hensbergen, Paul J; Sharp, Thomas H

Abendstein, Leoni; Dijkstra, Douwe J; Tjokrodirijo, Rayman T N; van Veelen, Peter A; Trouw, Leendert A; Hensbergen, Paul J; Sharp, Thomas H.

Afiliação

Abendstein L; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
Dijkstra DJ; Department of Immunology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.
Tjokrodirijo RTN; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.
van Veelen PA; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.
Trouw LA; Department of Immunology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.
Hensbergen PJ; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.
Sharp TH; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands. t.sharp@lumc.nl.

Nat Commun ; 14(1): 4027, 2023 07 07.

Article em En | MEDLINE | ID: mdl-37419978

Assuntos

Proteínas do Sistema Complemento; Imunoglobulina G; Ativação do Complemento; Antígenos; Complemento C1q/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Sistema Complemento / Imunoglobulina G Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda

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