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Regio- and stereoselective steroid hydroxylation by CYP109A2 from Bacillus megaterium explored by X-ray crystallography and computational modeling.
Józwik, Ilona K; Bombino, Elvira; Abdulmughni, Ammar; Hartz, Philip; Rozeboom, Henriette J; Wijma, Hein J; Kappl, Reinhard; Janssen, Dick B; Bernhardt, Rita; Thunnissen, Andy-Mark W H.
Afiliação
  • Józwik IK; Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.
  • Bombino E; Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.
  • Abdulmughni A; Department of Biochemistry, Saarland University, Saarbrücken, Germany.
  • Hartz P; Department of Biochemistry, Saarland University, Saarbrücken, Germany.
  • Rozeboom HJ; Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.
  • Wijma HJ; Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.
  • Kappl R; Department of Biophysics, CIPMM, School of Medicine, Saarland University, Saarbrücken, Germany.
  • Janssen DB; Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.
  • Bernhardt R; Department of Biochemistry, Saarland University, Saarbrücken, Germany.
  • Thunnissen AWH; Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.
FEBS J ; 290(20): 5016-5035, 2023 10.
Article em En | MEDLINE | ID: mdl-37453052
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacillus megaterium / Sistema Enzimático do Citocromo P-450 Tipo de estudo: Prognostic_studies Idioma: En Revista: FEBS J Assunto da revista: BIOQUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda
Texto completo
Adicionar na Minha BVS
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacillus megaterium / Sistema Enzimático do Citocromo P-450 Tipo de estudo: Prognostic_studies Idioma: En Revista: FEBS J Assunto da revista: BIOQUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda