Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in murine Alzheimer's disease.

Tallon, Carolyn; Bell, Benjamin J; Malvankar, Medhinee M; Deme, Pragney; Nogueras-Ortiz, Carlos; Eren, Erden; Thomas, Ajit G; Hollinger, Kristen R; Pal, Arindom; Mustapic, Maja; Huang, Meixiang; Coleman, Kaleem; Joe, Tawnjerae R; Rais, Rana; Haughey, Norman J; Kapogiannis, Dimitrios; Slusher, Barbara S

Tallon, Carolyn; Bell, Benjamin J; Malvankar, Medhinee M; Deme, Pragney; Nogueras-Ortiz, Carlos; Eren, Erden; Thomas, Ajit G; Hollinger, Kristen R; Pal, Arindom; Mustapic, Maja; Huang, Meixiang; Coleman, Kaleem; Joe, Tawnjerae R; Rais, Rana; Haughey, Norman J; Kapogiannis, Dimitrios; Slusher, Barbara S.

Afiliação

Tallon C; Johns Hopkins University.
Bell BJ; Johns Hopkins University.
Malvankar MM; Johns Hopkins University.
Deme P; Johns Hopkins University.
Nogueras-Ortiz C; National Institute on Aging Laboratory of Clinical Investigation.
Eren E; National Institute on Aging Laboratory of Clinical Investigation.
Thomas AG; Johns Hopkins University.
Hollinger KR; Johns Hopkins University.
Pal A; Johns Hopkins University.
Mustapic M; National Institute on Aging Laboratory of Clinical Investigation.
Huang M; Johns Hopkins University.
Coleman K; Johns Hopkins University.
Joe TR; Johns Hopkins University.
Rais R; Johns Hopkins University.
Haughey NJ; Johns Hopkins University.
Kapogiannis D; National Institute on Aging Laboratory of Clinical Investigation.
Slusher BS; Johns Hopkins University.

Res Sq ; 2023 Jul 18.

Article em En | MEDLINE | ID: mdl-37502930

Palavras-chave

Alzheimer's disease; ceramide; extracellular vesicles; neutral sphingomyelinase 2; tau

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Res Sq Ano de publicação: 2023 Tipo de documento: Article