Dioscin ameliorates doxorubicin-induced heart failure via inhibiting autophagy and apoptosis by controlling the PDK1-mediated Akt/mTOR signaling pathway.

Yuan, Ling; Ji, Hai-Gang; Yan, Xiao-Jing; Liu, Meng; Ding, Yu-Han; Chen, Xiao-Hu

Yuan, Ling; Ji, Hai-Gang; Yan, Xiao-Jing; Liu, Meng; Ding, Yu-Han; Chen, Xiao-Hu.

Afiliação

Yuan L; Department of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Ji HG; Department of Cardiology, Changzhou Hospital Affiliated to Nanjing University of Chinese Medicine, Changzhou, China.
Yan XJ; Department of Cardiology, Changzhou Hospital Affiliated to Nanjing University of Chinese Medicine, Changzhou, China.
Liu M; Changzhou Key Laboratory of Human Use Experience Research & Transformation of Menghe Medical School, Changzhou Hospital Affiliated to Nanjing University of Chinese Medicine, Changzhou, China.
Ding YH; Department of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Chen XH; Department of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.

Kaohsiung J Med Sci ; 39(10): 1022-1029, 2023 Oct.

Article em En | MEDLINE | ID: mdl-37578093

Palavras-chave

Akt/mTOR; Dioscin; PDK1; doxorubicin; heart failure

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 2_muertes_prematuras_enfermedades_notrasmisibles / 6_cardiovascular_diseases / 6_other_circulatory_diseases Idioma: En Revista: Kaohsiung J Med Sci Assunto da revista: MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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