Combination Therapy with Ciprofloxacin and Pentamidine against Multidrug-Resistant <i>Pseudomonas aeruginosa</i>: Assessment of In Vitro and In Vivo Efficacy and the Role of Resistance-Nodulation-Division (RND) Efflux Pumps.

Fletcher, Megan; McCormack, Alex; Parcell, Benjamin J; Coote, Peter J

Combination Therapy with Ciprofloxacin and Pentamidine against Multidrug-Resistant Pseudomonas aeruginosa: Assessment of In Vitro and In Vivo Efficacy and the Role of Resistance-Nodulation-Division (RND) Efflux Pumps.

Fletcher, Megan; McCormack, Alex; Parcell, Benjamin J; Coote, Peter J.

Afiliação

Fletcher M; Biomedical Sciences Research Complex, School of Biology, University of St Andrews, The North Haugh, St Andrews, Fife KY16 9ST, UK.
McCormack A; Biomedical Sciences Research Complex, School of Biology, University of St Andrews, The North Haugh, St Andrews, Fife KY16 9ST, UK.
Parcell BJ; NHS Tayside, Medical Microbiology, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
Coote PJ; Biomedical Sciences Research Complex, School of Biology, University of St Andrews, The North Haugh, St Andrews, Fife KY16 9ST, UK.

Antibiotics (Basel) ; 12(8)2023 Jul 26.

Article em En | MEDLINE | ID: mdl-37627656

Palavras-chave

Galleria mellonella; MexAB-OprM; antibiotic resistance; antibiotic resistance breaker; drug repurposing; efflux pump inhibitor; synergy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Antibiotics (Basel) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido

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