Aldehyde dehydrogenase 2 deficiency reinforces formaldehyde-potentiated pro-inflammatory responses and glycolysis in macrophages.

Ma, Huijuan; Lou, Kaiyan; Shu, Qi; Song, Xiaodong; Xu, Huan

Ma, Huijuan; Lou, Kaiyan; Shu, Qi; Song, Xiaodong; Xu, Huan.

Afiliação

Ma H; Shanghai Key Laboratory of New Drug Design, State Key Laboratory of Bioreactor Engineering, School of Pharmacy, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, East China University of Science and Technology, Shanghai, China.
Lou K; Shanghai Key Laboratory of New Drug Design, State Key Laboratory of Bioreactor Engineering, School of Pharmacy, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, East China University of Science and Technology, Shanghai, China.
Shu Q; Shanghai Key Laboratory of New Drug Design, State Key Laboratory of Bioreactor Engineering, School of Pharmacy, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, East China University of Science and Technology, Shanghai, China.
Song X; Medical Laboratory Department, Hua Shan Hospital North, Fudan University, Shanghai, China.
Xu H; Shanghai Key Laboratory of New Drug Design, State Key Laboratory of Bioreactor Engineering, School of Pharmacy, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, East China University of Science and Technology, Shanghai, China.

J Biochem Mol Toxicol ; 38(1): e23518, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37638564

Assuntos

Acetaldeído; Etanol; Humanos; Camundongos; Animais; Aldeído-Desidrogenase Mitocondrial/genética; Etanol/toxicidade; Acetaldeído/toxicidade; Formaldeído/toxicidade; Camundongos Knockout; Macrófagos

Palavras-chave

ALDH2; HIF-1α; glycolysis; inflammatory cytokines; macrophages

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Etanol / Acetaldeído Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biochem Mol Toxicol Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA / TOXICOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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