Injection of exogenous amyloid-ß oligomers aggravated cognitive deficits, and activated necroptosis, in APP23 transgenic mice.

Yu, Haibo; Morihara, Ryuta; Ota-Elliott, Ricardo; Bian, Zhihong; Bian, Yuting; Hu, Xinran; Sun, Hongming; Fukui, Yusuke; Abe, Koji; Ishiura, Hiroyuki; Yamashita, Toru

Yu, Haibo; Morihara, Ryuta; Ota-Elliott, Ricardo; Bian, Zhihong; Bian, Yuting; Hu, Xinran; Sun, Hongming; Fukui, Yusuke; Abe, Koji; Ishiura, Hiroyuki; Yamashita, Toru.

Afiliação

Yu H; Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Morihara R; Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Ota-Elliott R; Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Bian Z; Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Bian Y; Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Hu X; Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Sun H; Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Fukui Y; Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Abe K; National Center Hospital, National Center of Neurology and Psychiatry, Kodaira-shi, Tokyo, Japan.
Ishiura H; Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Yamashita T; Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. Electronic address: toruyamashita@okayama-u.ac.jp.

Brain Res ; 1821: 148565, 2023 12 15.

Article em En | MEDLINE | ID: mdl-37683777

Assuntos

Doença de Alzheimer; Disfunção Cognitiva; Doenças Neurodegenerativas; Camundongos; Animais; Peptídeos beta-Amiloides/metabolismo; Camundongos Transgênicos; Necroptose; Doença de Alzheimer/metabolismo; Disfunção Cognitiva/induzido quimicamente; Cognição

Palavras-chave

Alzheimer's disease (AD); Amyloid-ß oligomers (AßO); Microglia; Necroptosis; Neurodegeneration

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Neurodegenerativas / Doença de Alzheimer / Disfunção Cognitiva Limite: Animals Idioma: En Revista: Brain Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

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