Structural Modification of the Natural Product Valerenic Acid Tunes RXR Homodimer Agonism.

Zaienne, Daniel; Isigkeit, Laura; Marschner, Julian A; Duensing-Kropp, Silke; Höfner, Georg; Merk, Daniel

Zaienne, Daniel; Isigkeit, Laura; Marschner, Julian A; Duensing-Kropp, Silke; Höfner, Georg; Merk, Daniel.

Afiliação

Zaienne D; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt, Germany.
Isigkeit L; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt, Germany.
Marschner JA; Department of Pharmacy, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377, Munich, Germany.
Duensing-Kropp S; Department of Pharmacy, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377, Munich, Germany.
Höfner G; Department of Pharmacy, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377, Munich, Germany.
Merk D; Department of Pharmacy, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377, Munich, Germany.

ChemMedChem ; 18(21): e202300404, 2023 11 02.

Article em En | MEDLINE | ID: mdl-37697963

Assuntos

Indenos; Sesquiterpenos; Indenos/farmacologia; Receptores X de Retinoides/metabolismo; Receptores Citoplasmáticos e Nucleares

Palavras-chave

cancer; natural product synthesis; neurodegeneration; retinoid X receptor; transcription factor

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sesquiterpenos / Indenos Tipo de estudo: Prognostic_studies Idioma: En Revista: ChemMedChem Assunto da revista: FARMACOLOGIA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google