Synthesis and cytotoxicity evaluation of novel 1,8-acridinedione derivatives bearing phthalimide moiety as potential antitumor agents.

Khatab, Hassan A; Hammad, Sherif F; El-Fakharany, Esmail M; Hashem, Ahmed I; El-Helw, Eman A E

Khatab, Hassan A; Hammad, Sherif F; El-Fakharany, Esmail M; Hashem, Ahmed I; El-Helw, Eman A E.

Afiliação

Khatab HA; Egypt-Japan University of Science and Technology (E-JUST), Alexandria, Egypt.
Hammad SF; Chemistry Department, Faculty of Science, Ain Shams University, Cairo, 11566, Egypt.
El-Fakharany EM; Egypt-Japan University of Science and Technology (E-JUST), Alexandria, Egypt.
Hashem AI; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
El-Helw EAE; Protein Research Department, Genetic Engineering and Biotechnology Research Institute GEBRI, City of Scientific Research and Technological Applications, New Borg El Arab, 21934, Alexandria, Egypt.

Sci Rep ; 13(1): 15093, 2023 09 12.

Article em En | MEDLINE | ID: mdl-37699954

Assuntos

Antineoplásicos; Proteína Supressora de Tumor p53; Humanos; Simulação de Acoplamento Molecular; Antineoplásicos/farmacologia; Ftalimidas/farmacologia; Receptores ErbB

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Antineoplásicos Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Egito

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