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Heterologous DNA-prime/protein-boost immunization with a monomeric SARS-CoV-2 spike antigen redundantizes the trimeric receptor-binding domain structure to induce neutralizing antibodies in old mice.
Pflumm, Dominik; Seidel, Alina; Klein, Fabrice; Groß, Rüdiger; Krutzke, Lea; Kochanek, Stefan; Kroschel, Joris; Münch, Jan; Stifter, Katja; Schirmbeck, Reinhold.
Afiliação
  • Pflumm D; Department of Internal Medicine I, University Hospital of Ulm, Ulm, Germany.
  • Seidel A; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Klein F; Department of Gene Therapy, University Hospital of Ulm, Ulm, Germany.
  • Groß R; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Krutzke L; Department of Gene Therapy, University Hospital of Ulm, Ulm, Germany.
  • Kochanek S; Department of Gene Therapy, University Hospital of Ulm, Ulm, Germany.
  • Kroschel J; Institute of Clinical Chemistry, Ulm University Medical Center, Ulm, Germany.
  • Münch J; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Stifter K; Department of Internal Medicine I, University Hospital of Ulm, Ulm, Germany.
  • Schirmbeck R; Department of Internal Medicine I, University Hospital of Ulm, Ulm, Germany.
Front Immunol ; 14: 1231274, 2023.
Article em En | MEDLINE | ID: mdl-37753087
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 / 4_TD Problema de saúde: 2_enfermedades_transmissibles / 4_pneumonia Assunto principal: Antígenos de Grupos Sanguíneos / Vacinas de DNA / COVID-19 Limite: Animals Idioma: En Revista: Front Immunol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 / 4_TD Problema de saúde: 2_enfermedades_transmissibles / 4_pneumonia Assunto principal: Antígenos de Grupos Sanguíneos / Vacinas de DNA / COVID-19 Limite: Animals Idioma: En Revista: Front Immunol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha