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Cross-protection of a porcine circovirus types 2a/b (PCV-2a/b) and Mycoplasma hyopneumoniae trivalent vaccine against a dual PCV-2e and Mycoplasma hyopneumoniae challenge.
Suh, Jeongmin; Ham, Sehyeong; Oh, Taehwan; Chae, Chanhee.
Afiliação
  • Suh J; Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
  • Ham S; Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
  • Oh T; Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
  • Chae C; Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Can J Vet Res ; 87(4): 297-302, 2023 Oct.
Article em En | MEDLINE | ID: mdl-37790269
ABSTRACT
The purpose of this experimental study was to determine the cross-protection of a new trivalent vaccine containing porcine circovirus types 2a/b (PCV-2a/b) and Mycoplasma hyopneumoniae. Pigs were vaccinated intramuscularly at 21 days of age, then challenged at 42 days of age with a dual PCV-2e and M. hyopneumoniae challenge. Growth performance was significantly improved during the experimental period (21 to 63 days of age) in vaccinated-challenged pigs compared to unvaccinated-challenged pigs. Pigs that were vaccinated and challenged elicited a significant amount of PCV-2e- and M. hyopneumoniae-specific interferon-γ secreting cells (IFN-γ-SC) and reduced the levels of PCV-2e viremia and laryngeal shedding. The results of the present study demonstrated that a trivalent vaccine provided cross-protection against a dual PCV-2e and M. hyopneumoniae challenge.
Le but de cette étude expérimentale était de déterminer la protection croisée d'un nouveau vaccin trivalent contenant le circovirus porcin de types 2a/b (PCV-2a/b) et Mycoplasma hyopneumoniae. Les porcs ont été vaccinés par voie intramusculaire à l'âge de 21 jours, puis provoqués à l'âge de 42 jours avec double provocation par PCV-2e et M. hyopneumoniae. Les performances de croissance ont été significativement améliorées au cours de la période expérimentale (21 à 63 jours) chez les porcs vaccinés-provoqués par rapport aux porcs non-vaccinés-provoqués. Les porcs qui ont été vaccinés et provoqués ont produit une quantité importante de cellules sécrétant de l'interféron-γ spécifiques au PCV-2e et à M. hyopneumoniae (IFN-γ-SC) et ont réduit les niveaux de virémie du PCV-2e et d'excrétion laryngée. Les résultats de la présente étude ont démontré qu'un vaccin trivalent offrait une protection croisée contre une double provocation par le PCV-2e et M. hyopneumoniae.(Traduit par Docteur Serge Messier).
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 Problema de saúde: 2_enfermedades_transmissibles Assunto principal: Doenças dos Suínos / Vacinas Virais / Circovirus / Infecções por Circoviridae / Mycoplasma hyopneumoniae Limite: Animals Idioma: En Revista: Can J Vet Res Assunto da revista: MEDICINA VETERINARIA Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 Problema de saúde: 2_enfermedades_transmissibles Assunto principal: Doenças dos Suínos / Vacinas Virais / Circovirus / Infecções por Circoviridae / Mycoplasma hyopneumoniae Limite: Animals Idioma: En Revista: Can J Vet Res Assunto da revista: MEDICINA VETERINARIA Ano de publicação: 2023 Tipo de documento: Article
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