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SARS-CoV-2 evolution in the Omicron era.
Roemer, Cornelius; Sheward, Daniel J; Hisner, Ryan; Gueli, Federico; Sakaguchi, Hitoshi; Frohberg, Nicholas; Schoenmakers, Josette; Sato, Kenta; O'Toole, Áine; Rambaut, Andrew; Pybus, Oliver G; Ruis, Christopher; Murrell, Ben; Peacock, Thomas P.
Afiliação
  • Roemer C; Biozentrum, University of Basel, Basel, Switzerland.
  • Sheward DJ; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Hisner R; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Gueli F; University of Cape Town, Rondebosch, South Africa.
  • Sakaguchi H; Independent researcher, Como, Italy.
  • Frohberg N; Independent researcher, Yotsukaido City, Japan.
  • Schoenmakers J; Independent researcher, Madison, WI, USA.
  • Sato K; Independent researcher, Haarlem, The Netherlands.
  • O'Toole Á; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Rambaut A; Institute of Ecology and Evolution, University of Edinburgh, Edinburgh, UK.
  • Pybus OG; Institute of Ecology and Evolution, University of Edinburgh, Edinburgh, UK.
  • Ruis C; Department of Biology, University of Oxford, Oxford, UK.
  • Murrell B; Department of Pathobiology and Population Science, Royal Veterinary College, London, UK.
  • Peacock TP; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge, UK.
Nat Microbiol ; 8(11): 1952-1959, 2023 Nov.
Article em En | MEDLINE | ID: mdl-37845314
Since SARS-CoV-2 BA.5 (Omicron) emerged and spread in 2022, Omicron lineages have markedly diversified. Here we review the evolutionary trajectories and processes that underpin the emergence of these lineages, and identify the most prevalent sublineages. We discuss the potential origins of second-generation BA.2 lineages. Simple and complex recombination, antigenic drift and convergent evolution have enabled SARS-CoV-2 to accumulate mutations that alter its antigenicity. We also discuss the potential evolutionary trajectories of SARS-CoV-2 in the future.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 Limite: Humans Idioma: En Revista: Nat Microbiol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 Limite: Humans Idioma: En Revista: Nat Microbiol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suíça