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Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
Prévost, Jérémie; Chen, Yaozong; Zhou, Fei; Tolbert, William D; Gasser, Romain; Medjahed, Halima; Nayrac, Manon; Nguyen, Dung N; Gottumukkala, Suneetha; Hessell, Ann J; Rao, Venigalla B; Pozharski, Edwin; Huang, Rick K; Matthies, Doreen; Finzi, Andrés; Pazgier, Marzena.
Afiliação
  • Prévost J; Centre de Recherche du CHUM, Montreal, QC, Canada.
  • Chen Y; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada.
  • Zhou F; Infectious Disease Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Tolbert WD; Unit on Structural Biology, Division of Basic and Translational Biophysics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
  • Gasser R; Infectious Disease Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Medjahed H; Centre de Recherche du CHUM, Montreal, QC, Canada.
  • Nayrac M; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada.
  • Nguyen DN; Centre de Recherche du CHUM, Montreal, QC, Canada.
  • Gottumukkala S; Centre de Recherche du CHUM, Montreal, QC, Canada.
  • Hessell AJ; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada.
  • Rao VB; Infectious Disease Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Pozharski E; Infectious Disease Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Huang RK; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
  • Matthies D; Department of Biology, the Catholic University of America, Washington, DC, USA.
  • Finzi A; Institute for Bioscience and Biotechnology Research, Rockville, MD, 20850, USA.
  • Pazgier M; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA.
Nat Commun ; 14(1): 6710, 2023 10 23.
Article em En | MEDLINE | ID: mdl-37872202

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / Fármacos Anti-HIV / Inibidores da Fusão de HIV Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / Fármacos Anti-HIV / Inibidores da Fusão de HIV Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá
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