Molecular Mechanisms of Ferroptosis and Their Involvement in Acute Kidney Injury.
J Inflamm Res
; 16: 4941-4951, 2023.
Article
em En
| MEDLINE
| ID: mdl-37936596
ABSTRACT
Ferroptosis is a novel way of regulating cell death, which occurs in a process that is closely linked to intracellular iron metabolism, lipid metabolism, amino acid metabolism, and multiple signaling pathways. The latest research shows that ferroptosis plays a key role in the pathogenesis of acute kidney injury (AKI). Ferroptosis may be an important target for treating AKI caused by various reasons, such as ischemia-reperfusion injury, rhabdomyolysis syndrome, sepsis, and nephrotoxic drugs. This paper provides a review on the regulatory mechanisms of ferroptosis and its role in AKI, which may help to provide new research ideas for the treatment of AKI and future research.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Inflamm Res
Ano de publicação:
2023
Tipo de documento:
Article