Leveraging genetic correlations and multiple populations to improve genetic risk prediction for non-European populations.

Xu, Leqi; Zhou, Geyu; Jiang, Wei; Guan, Leying; Zhao, Hongyu

Xu, Leqi; Zhou, Geyu; Jiang, Wei; Guan, Leying; Zhao, Hongyu.

Afiliação

Xu L; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
Zhou G; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
Jiang W; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
Guan L; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
Zhao H; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.

bioRxiv ; 2023 Dec 12.

Article em En | MEDLINE | ID: mdl-37961111

Palavras-chave

Bayesian high-dimensional regression; Continuous shrinkage prior; Cross-population genetic correlation; Multi-population genetic risk prediction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 Problema de saúde: 1_desigualdade_iniquidade Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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