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Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation.
Cortés, Marlies; Brischetto, Agnese; Martinez-Campanario, M C; Ninfali, Chiara; Domínguez, Verónica; Fernández, Sara; Celis, Raquel; Esteve-Codina, Anna; Lozano, Juan J; Sidorova, Julia; Garrabou, Gloria; Siegert, Anna-Maria; Enrich, Carlos; Pintado, Belén; Morales-Ruiz, Manuel; Castro, Pedro; Cañete, Juan D; Postigo, Antonio.
Afiliação
  • Cortés M; Group of Gene Regulation in Stem Cells, Cell Plasticity, Differentiation, and Cancer, IDIBAPS, 08036, Barcelona, Spain. mcortesh@recerca.clinic.cat.
  • Brischetto A; Group of Gene Regulation in Stem Cells, Cell Plasticity, Differentiation, and Cancer, IDIBAPS, 08036, Barcelona, Spain.
  • Martinez-Campanario MC; Group of Gene Regulation in Stem Cells, Cell Plasticity, Differentiation, and Cancer, IDIBAPS, 08036, Barcelona, Spain.
  • Ninfali C; Group of Gene Regulation in Stem Cells, Cell Plasticity, Differentiation, and Cancer, IDIBAPS, 08036, Barcelona, Spain.
  • Domínguez V; National Center of Biotechnology (CSIC-CNB) and Center for Molecular Biology Severo Ochoa (CSIC/UAM-CBMSO) Transgenesis Facility, Higher Research Council (CSIC) and Autonomous University of Madrid (UAM), Cantoblanco, 28049, Madrid, Spain.
  • Fernández S; Medical Intensive Care Unit and Department of Internal Medicine, Hospital Clínic of Barcelona, Group of Muscle Research and Mitochondrial Function, IDIBAPS, and CIBERER, 08036, Barcelona, Spain.
  • Celis R; Arthritis Unit, Dept. of Rheumathology, Hospital Clínic and IDIBAPS, 08036, Barcelona, Spain.
  • Esteve-Codina A; National Center for Genomics Analysis (CNAG), 08028, Barcelona, Spain.
  • Lozano JJ; Biomedical Research Networking Centers in Digestive and Hepatic Diseases (CIBERehd), Carlos III Health Institute, 08036, Barcelona, Spain.
  • Sidorova J; Biomedical Research Networking Centers in Digestive and Hepatic Diseases (CIBERehd), Carlos III Health Institute, 08036, Barcelona, Spain.
  • Garrabou G; Medical Intensive Care Unit and Department of Internal Medicine, Hospital Clínic of Barcelona, Group of Muscle Research and Mitochondrial Function, IDIBAPS, and CIBERER, 08036, Barcelona, Spain.
  • Siegert AM; MRC Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, CB1 0QQ, UK.
  • Enrich C; Department of Biomedicine, University of Barcelona School of Medicine and Health Sciences, 08036, Barcelona, Spain.
  • Pintado B; National Center of Biotechnology (CSIC-CNB) and Center for Molecular Biology Severo Ochoa (CSIC/UAM-CBMSO) Transgenesis Facility, Higher Research Council (CSIC) and Autonomous University of Madrid (UAM), Cantoblanco, 28049, Madrid, Spain.
  • Morales-Ruiz M; Biomedical Research Networking Centers in Digestive and Hepatic Diseases (CIBERehd), Carlos III Health Institute, 08036, Barcelona, Spain.
  • Castro P; Department of Biomedicine, University of Barcelona School of Medicine and Health Sciences, 08036, Barcelona, Spain.
  • Cañete JD; Department of Biochemistry and Molecular Genetics, Hospital Clínic of Barcelona and IDIBAPS, 08036, Barcelona, Spain.
  • Postigo A; Medical Intensive Care Unit and Department of Internal Medicine, Hospital Clínic of Barcelona, Group of Muscle Research and Mitochondrial Function, IDIBAPS, and CIBERER, 08036, Barcelona, Spain.
Nat Commun ; 14(1): 7471, 2023 11 17.
Article em En | MEDLINE | ID: mdl-37978290
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Macrófagos / Metformina Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Espanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Macrófagos / Metformina Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Espanha