Sesamin inhibits RANKL-induced osteoclastogenesis and attenuates LPS-induced osteolysis via suppression of ERK and NF-&#954;B signalling pathways.

Yu, Xiaolong; Hu, Jiawei; Yang, Xinming; Xu, Qiang; Chen, Hangjun; Zhan, Ping; Zhang, Bin

Sesamin inhibits RANKL-induced osteoclastogenesis and attenuates LPS-induced osteolysis via suppression of ERK and NF-κB signalling pathways.

Yu, Xiaolong; Hu, Jiawei; Yang, Xinming; Xu, Qiang; Chen, Hangjun; Zhan, Ping; Zhang, Bin.

Afiliação

Yu X; Orthopedics Department, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center, Nanchang, China.
Hu J; Orthopedics Department, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center, Nanchang, China.
Yang X; Orthopedics Department, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center, Nanchang, China.
Xu Q; Orthopedics Department, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center, Nanchang, China.
Chen H; Orthopedics Department, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center, Nanchang, China.
Zhan P; Orthopedics Department, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center, Nanchang, China.
Zhang B; Orthopedics Department, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center, Nanchang, China.

J Cell Mol Med ; 28(2): e18056, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37988238

Assuntos

Reabsorção Óssea; Dioxóis; Lignanas; Osteólise; Humanos; Animais; Camundongos; Osteólise/induzido quimicamente; Osteólise/tratamento farmacológico; NF-kappa B/metabolismo; Osteogênese; Lipopolissacarídeos/metabolismo; Osteoclastos/metabolismo; Reabsorção Óssea/patologia; Inflamação/patologia; Citocinas/metabolismo; Ligante RANK/metabolismo; Camundongos Endogâmicos C57BL

Palavras-chave

ERK; NF-κB; Osteolysis; Sesamin; osteoclast

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteólise / Reabsorção Óssea / Lignanas / Dioxóis Limite: Animals / Humans Idioma: En Revista: J Cell Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google